How DHEA Lowers Male Testosterone
By Dr. David Ryan & Dr. Richard Cavender
Many nutritional supplements hit the shelves claiming to offer improved health and function. Some items fall significantly short of their marketing claims.
DHEA (dehyropiandrosterone) is one such supplement that claims to raise male testosterone levels naturally. The marketing of these products offers multiple claims of improving muscle mass and erectile dysfunction. The claims of DHEA preventing the metabolic changes typically associated with aging, but no actual studies have been published by universities to verify any benefit.
The main issue with this supplement is related to the natural feedback mechanism that occurs in the body with the presence of elevated DHEA. The DHEA aromatizes to esterone, which provides negative feedback to the anterior pituitary to suppress luteinizing hormone, which removes the positive stimulate production of the testicular production of testosterone.
This process is visible through several years of blood studies and clinical case studies. Some of the production of DHEA is from plant based items such as yams, this offers bio-identification problems in the human body and also other hypersensitivity issues with many men.
The majority of DHEA is produced from cholesterol that is adjusted by several enzymes. This produces less bio-mechanical interruption and allows for more appropriate absorption.
DHEA is thought to regulate some proteins via indirect mechanisms. In most cases the studies have failed to show an increase in lean muscle mass any greater than placebo in men.
All is not lost. Women have a significant benefit from taking DHEA since it has been shown to aromatize in them and result in a testosterone byproduct. This occurs in roughly 95% of all females who use DHEA.
Female reproductive health has noted a significant improvement with treating female infertility with a combination of gonadotrophins and DHEA.
Lupus is a very difficult disease and effects more women than men. Short term benefits are noted, but there is some concern with long term issues.
Although DHEA has been used by the public and it’s safety is well noted for the past 15 years. Since DHEA occurs naturally in the body, there is little rise for concern and dosages as high as 2.250 grams per day for 2 years still with no adverse side effects, but this study didn’t test for actual testosterone production in the males.
The World anti-doping Agency is responsible for drug testing at the Olympics and they have marked DHEA for the prohibited substance list.
So to summarize, the simple concern is with DHEA lowering testosterone in the male, but the female who specifically has depression and adrenal fatigue, appear to benefit from it’s use.
Yours in Health!
Dr. David Ryan & Dr. Richard Cavender
Columbus Chiropractic Center Director
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